PORCN Inhibitor Market, Industry Trends, Size, and Forecast to 2033

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2026-01-19 19:16:55 -

PORCN inhibitors are small-molecule drugs targeting the Porcupine (PORCN) enzyme, a key component of the Wnt signaling pathway. The Wnt pathway regulates cell proliferation, differentiation, and survival, and its aberrant activation drives oncogenesis in cancers like colorectal (30–40% Wnt-activated), pancreatic, and breast cancers. PORCN palmitoylates Wnt ligands, enabling their...

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