🔬 Predictive Modeling for ADMET Properties to Mitigate Drug Failure...

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2025-12-04 13:11:47 -

🔬 Predictive Modeling for ADMET Properties to Mitigate Drug Failure in Later Clinical Stages

Moving Beyond Efficacy to Assess the Critical Pharmacokinetic and Safety Profile A significant reason for the high failure rate of potential therapeutic agents in human trials is not a lack of efficacy, but poor Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) properties. Computational simulation allows these crucial safety and pharmacokinetic hurdles to be assessed...

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